منابع مشابه
Inhaled insulin: promises and concerns.
Since the introduction of Pfizer Exubera in the early 1990s, a number of other inhaled insulin solutions have been developed. This article provides an overview of inhaled insulin systems developed by Pfizer, Novo Nordisk, MannKind, and Lilly, three of which are currently in phase 3 trials. The strengths and weaknesses of each product, as well as the general technologies (liquid vs dry powder), ...
متن کاملInsulin Concerns and Promises
DIABETES, INSULIN, AND CANCER—At a symposium discussing controversies pertaining to relationships between diabetes and cancer, Jeffrey A. Johnson (Edmonton, Canada) reviewed epidemiologic data, beginning with a meta-analysis showing that diabetes is associated with increased rates of cancers of the pancreas, colon and rectum, bladder, liver, and breast; endometrial cancer; and non-Hodgkin’s lym...
متن کاملPrandial Insulin: Is Inhaled Enough?
The low proportion of patients achieving glycemic targets is well documented for both type 1 and type 2 diabetes. Postprandial glucose levels are often not monitored but contribute significantly to total glycemic burden. Prandial rapid-acting insulin analogues were introduced to address some of these problems but still do not provide a physiologic insulin replacement. Inhaled prandial insulins ...
متن کاملInhaled insulin in diabetes mellitus.
BACKGROUND Insulin therapy often relies on multiple daily injections of insulin. However this is a considerable burden to many people with diabetes and adherence to such an insulin regimen can be difficult to maintain, hence compromising optimal glycaemic control. Also, short acting injected insulin is absorbed more slowly than insulin released by the normal pancreas in response to a meal. Inha...
متن کاملInhaled insulin: overview of a novel route of insulin administration
Diabetes is a chronic disease characterized by inadequate insulin secretion with resulting hyperglycemia. Diabetes complications include both microvascular and macrovascular disease, both of which are affected by optimal diabetes control. Many individuals with diabetes rely on subcutaneous insulin administration by injection or continuous infusion to control glucose levels. Novel routes of insu...
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ژورنال
عنوان ژورنال: BMJ
سال: 2006
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.332.7552.1273-e